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1

[6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo

Kim, Jin-Kyoung, Kim, Younghwa, Na, Kwang-Min, Surh, Young-Joon, Kim, Tae-Yoon

Journal:

Free Radical Research

Année:

2007

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2007

2

Design and commissioning of magnetic diagnostics in VEST

Lee, Jeongwon, Chung, Kyoung-Jae, An, YoungHwa, Jeong-hun, Yang, Kim, Young-gi, Jung, Bong-Ki, Hwang, Y.S., Hahm, T.S., Na, Yong-Su

Journal:

Fusion Engineering and Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2013

3

A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study

Karki, Radha, Jun, Kyu-Yeon, Kadayat, Tara Man, Shin, Somin, Thapa Magar, Til Bahadur, Bist, Ganesh, Shrestha, Aarajana, Na, Younghwa, Kwon, Youngjoo, Lee, Eung-Seok

Journal:

European Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2016

4

SLEEP QUALITY IN YOUNG AND MIDDLE AGE-PERIOD IS ASSOCIATED WITH CEREBRAL AMYLOID BURDEN IN COGNITIVELY NORMAL ELDERLY PEOPLE

Choe, Young Min, Byun, Min Soo, Yi, Dahyun, Choi, Hyo Jung, Baek, Hyewon, Lee, Jun Ho, Kim, Hyun Jung, Sohn, Bo Kyung, Kim, Jee Wook, Lee, Younghwa, Ko, Hyunwoong, Han, Na Young, Lee, Seung Hoon, Ko,

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 196 KB

english, 2016

5

ChemInform Abstract: A Concise Synthesis of Licochalcone E (VII) and Its Regioisomer, Licochalcone F (VIII)

Younghwa Na, Jeong-Heon Cha, Ho-Geun Yoon, Youngjoo Kwon

Journal:

Année:

2009

Fichier:

PDF, 31 KB

2009

6

ChemInform Abstract: 4-Hydroxy-2′-nitrodiphenyl Ether Analogues as Novel Tyrosinase Inhibitors.

Kiran Sapkota, Eunyoung Lee, Jae-Ho Yang, Youngjoo Kwon, Jongwon Choi, Younghwa Na

Journal:

Année:

2010

Fichier:

PDF, 18 KB

2010

7

Synthesis of new xanthone analogues and their biological activity test—Cytotoxicity, topoisomerase II inhibition, and DNA cross-linking study

Sangwook Woo, Ji Jung, Chongsoon Lee, Youngjoo Kwon, Younghwa Na

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 192 KB

english, 2007

8

2,4,6-Trisubstituted pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship

Arjun Basnet, Pritam Thapa, Radha Karki, Younghwa Na, Yurngdong Jahng, Byeong-Seon Jeong, Tae Cheon Jeong, Chong-Soon Lee, Eung-Seok Lee

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 332 KB

english, 2007

9

2-Thienyl-4-furyl-6-aryl pyridine derivatives: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study

Pritam Thapa, Radha Karki, Uttam Thapa, Yurngdong Jahng, Mi-Ja Jung, Jung Min Nam, Younghwa Na, Youngjoo Kwon, Eung-Seok Lee

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 456 KB

english, 2010

10

New benzoxanthone derivatives as topoisomerase inhibitors and DNA cross-linkers

Hee-Ju Cho, Mi-Ja Jung, Sangwook Woo, Jungsook Kim, Eung-Seok Lee, Youngjoo Kwon, Younghwa Na

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 357 KB

english, 2010

11

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines

Radha Karki, Pritam Thapa, Mi Jeong Kang, Tae Cheon Jeong, Jung Min Nam, Hye-Lin Kim, Younghwa Na, Won-Jea Cho, Youngjoo Kwon, Eung-Seok Lee

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 663 KB

english, 2010

12

Synthesis and anti-melanogenic activity of hydroxyphenyl benzyl ether analogues

Kiran Sapkota, Eunmiri Roh, Eunyoung Lee, Eun-Mi Ha, Jae-Ho Yang, Eung-Seok Lee, Youngjoo Kwon, Youngsoo Kim, Younghwa Na

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 262 KB

english, 2011

13

New insight for fluoroquinophenoxazine derivatives as possibly new potent topoisomerase I inhibitor

Da-Hye Kang, Jung-Sook Kim, Mi-Ja Jung, Eung-Seok Lee, Yurngdong Jahng, Youngjoo Kwon, Younghwa Na

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 153 KB

english, 2008

14

Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors

Hee-Ju Cho, Mi-Ja Jung, Youngjoo Kwon, Younghwa Na

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 249 KB

english, 2009

15

2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure–activity relationship, and docking study

Arjun Basnet, Pritam Thapa, Radha Karki, Hoyoung Choi, Jae Hun Choi, Minho Yun, Byeong-Seon Jeong, Yurngdong Jahng, Younghwa Na, Won-Jea Cho, Youngjoo Kwon, Chong-Soon Lee, Eung-Seok Lee

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 670 KB

english, 2010

16

Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivatives

Younghwa Na, Jung-Min Nam

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 279 KB

english, 2011

17

Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities

Jong-Keun Son, Long-Xuan Zhao, Arjun Basnet, Pritam Thapa, Radha Karki, Younghwa Na, Yurngdong Jahng, Tae Cheon Jeong, Byeong-Seon Jeong, Chong-Soon Lee, Eung-Seok Lee

Journal:

European Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 447 KB

english, 2008

18

Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship

Uttam Thapa, Pritam Thapa, Radha Karki, Minho Yun, Jae Hun Choi, Yurngdong Jahng, Eunyoung Lee, Kyung-Hwa Jeon, Younghwa Na, Eun-Mi Ha, Won-Jea Cho, Youngjoo Kwon, Eung-Seok Lee

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 507 KB

english, 2011

19

Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship

Pritam Thapa, Radha Karki, Hoyoung Choi, Jae Hun Choi, Minho Yun, Byeong-Seon Jeong, Mi-Ja Jung, Jung Min Nam, Younghwa Na, Won-Jea Cho, Youngjoo Kwon, Eung-Seok Lee

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 440 KB

english, 2010

20

Synthesis and pharmacological evaluation of new methyloxiranylmethoxyxanthone analogues

Sangwook Woo, Da-hye Kang, Jung Min Nam, Chong Soon Lee, Eun-Mi Ha, Eung-Seok Lee, Youngjoo Kwon, Younghwa Na

Journal:

European Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 396 KB

english, 2010

21

Synthesis, biological evaluation, and molecular docking study of 3-(3′-heteroatom substituted-2′-hydroxy-1′-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor

Kyu-Yeon Jun, Eun-Young Lee, Mi-Ja Jung, Ok-Hee Lee, Eung-Seok Lee, Hea-Young Park Choo, Younghwa Na, Youngjoo Kwon

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 527 KB

english, 2011

22

High density peptide microarrays. In situ synthesis and applications

Xiaolian Gao, Jean Philippe Pellois, Younghwa Na, Younkee Kim, Erdogan Gulari, Xiaochuan Zhou

Journal:

Molecular Diversity

Année:

2004

Langue:

english

Fichier:

PDF, 237 KB

english, 2004

23

Recent cancer drug development with xanthone structures

Journal:

Journal of Pharmacy and Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 165 KB

english, 2009

24

Identification of 3-Acetyl-2-aminoquinolin-4-one as a Novel, Nonpeptidic Scaffold for Specific Calpain Inhibitory Activity

Kang, Da-Hye, Jun, Kyu-Yeon, Lee, Jin Pyo, Pak, Chwang Siek, Na, Younghwa, Kwon, Youngjoo

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 283 KB

english, 2009

25

Synthesis, DNA Cross-Linking Activity, and Cytotoxicity of Dimeric Mitomycins

Na, Younghwa, Li, Ven-Shun, Nakanishi, Yuka, Bastow, Kenneth F., Kohn, Harold

Journal:

Journal of Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 163 KB

english, 2001

26

2,4-Diaryl-5,6-dihydro-1,10-phenanthroline and 2,4-diaryl-5,6-dihydrothieno[2,3-h] quinoline derivatives for topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study

Pritam Thapa, Radha Karki, Han Young Yoo, Pil-Hoon Park, Eunyoung Lee, Kyung-Hwa Jeon, Younghwa Na, Won-Jea Cho, Youngjoo Kwon, Eung-Seok Lee

Journal:

Bioorganic Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 615 KB

english, 2012

27

Design, synthesis, and antitumor evaluation of 2,4,6-triaryl pyridines containing chlorophenyl and phenolic moiety

Pritam Thapa, Radha Karki, Minho Yun, Tara Man Kadayat, Eunyoung Lee, Han Byeol Kwon, Younghwa Na, Won-Jea Cho, Nam Doo Kim, Byeong-Seon Jeong, Youngjoo Kwon, Eung-Seok Lee

Journal:

European Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2012

28

Licochalcone E has an antidiabetic effect

Hong Gyu Park, Eun Jung Bak, Gye-Hyeong Woo, Jin Moon Kim, Zhejiu Quan, Jung Mogg Kim, Ho-Kun Yoon, Seung Hoon Cheon, Goo Yoon, Yun-Jung Yoo, Younghwa Na, Jeong-Heon Cha

Journal:

The Journal of Nutritional Biochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2012

29

Synthetic Enantiopure Aziridinomitosenes: Preparation, Reactivity, and DNA Alkylation Studies

Vedejs, Edwin, Naidu, B. N., Klapars, Artis, Warner, Don L., Li, Ven-shun, Na, Younghwa, Kohn, Harold

Journal:

Journal of the American Chemical Society

Année:

2003

Langue:

english

Fichier:

PDF, 294 KB

english, 2003

30

A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2

Hye-Lin Kim, Kyung-Hwa Jeon, Kyu-Yeon Jun, Yongmun Choi, Dae-Kee Kim, Younghwa Na, Youngjoo Kwon

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 495 KB

english, 2012

31

Design, Synthesis, and Evaluation of Psorospermin/Quinobenzoxazine Hybrids as Structurally Novel Antitumor Agents

Kim, Mu-Yong, Na, Younghwa, Vankayalapati, Hariprasad, Gleason-Guzman, Mary, Hurley, Laurence H.

Journal:

Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 504 KB

english, 2003

32

Chalcones, inhibitors for topoisomerase I and cathepsin B and L, as potential anti-cancer agents

Kim, Seok-Ho, Lee, Eunyoung, Baek, Kyung Hye, Kwon, Han Byeol, Woo, Hyunjung, Lee, Eung-Seok, Kwon, Youngjoo, Na, Younghwa

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 492 KB

english, 2013

33

Synthesis and investigation of dihydroxychalcones as calpain and cathepsin inhibitors

Baek, Kyung Hye, Karki, Radha, Lee, Eung-Seok, Na, Younghwa, Kwon, Youngjoo

Journal:

Bioorganic Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 548 KB

english, 2013

34

3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage

Park, So-Eun, Chang, In-Hye, Jun, Kyu-Yeon, Lee, Eunyoung, Lee, Eung-Seok, Na, Younghwa, Kwon, Youngjoo

Journal:

European Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 852 KB

english, 2013

35

5196312 Method and test composition for determination of enzyme activity

Nam, Jung Min, Jeon, Kyung-Hwa, Kwon, Hanbyeol, Lee, Eunyoung, Jun, Kyu-Yeon, Jin, Yeung Bae, Lee, Yun-Sil, Na, Younghwa, Kwon, Youngjoo

Journal:

Biotechnology Advances

Année:

1994

Langue:

english

Fichier:

PDF, 65 KB

english, 1994

36

Editorial

Nam, Jung Min, Jeon, Kyung-Hwa, Kwon, Hanbyeol, Lee, Eunyoung, Jun, Kyu-Yeon, Jin, Yeung Bae, Lee, Yun-Sil, Na, Younghwa, Kwon, Youngjoo

Journal:

Clinical and Diagnostic Virology

Année:

1998

Langue:

english

Fichier:

PDF, 46 KB

english, 1998

37

Dithiiranylmethyloxy azaxanthone shows potent anti-tumor activity via suppression of HER2 expression and HER2-mediated signals in HER2-overexpressing breast cancer cells

Nam, Jung Min, Jeon, Kyung-Hwa, Kwon, Hanbyeol, Lee, Eunyoung, Jun, Kyu-Yeon, Jin, Yeung Bae, Lee, Yun-Sil, Na, Younghwa, Kwon, Youngjoo

Journal:

European Journal of Pharmaceutical Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2013

38

Control and data acquisition system for versatile experiment spherical torus at SNU

An, YoungHwa, Chung, Kyoung-Jae, Na, DongHyeon, Hwang, Y.S.

Journal:

Fusion Engineering and Design

Année:

2013

Langue:

english

Fichier:

PDF, 581 KB

english, 2013

39

7- N -(Mercaptoalkyl)mitomycins: Implications of Cyclization for Drug Function

Na, Younghwa, Wang, Shuang, Kohn, Harold

Journal:

Journal of the American Chemical Society

Année:

2002

Langue:

english

Fichier:

PDF, 194 KB

english, 2002

40

Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor

Jin, Cheng-Hao, Jun, Kyu-Yeon, Lee, Eunjung, Kim, Seongrak, Kwon, Youngjoo, Kim, Kunhong, Na, Younghwa

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 4.63 MB

english, 2014

41

Xanthone analogues as potent modulators of intestinal P-glycoprotein

Chae, Song Wha, Woo, Sangwook, Park, Jung Hyun, Kwon, Youngjoo, Na, Younghwa, Lee, Hwa Jeong

Journal:

European Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2015

42

A Series of Novel Terpyridine-Skeleton Molecule Derivants Inhibit Tumor Growth and Metastasis by Targeting Topoisomerases

Kwon, Han-Byeol, Park, Chanmi, Jeon, Kyung-Hwa, Lee, Eunyoung, Park, So-Eun, Jun, Kyu-Yeon, Kadayat, Tara Man, Thapa, Pritam, Karki, Radha, Na, Younghwa, Park, Mi Sun, Rho, Seung Bae, Lee, Eung-Seok,

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.79 MB

english, 2015

43

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines

Kadayat, Tara Man, Song, Chanju, Shin, Somin, Magar, Til Bahadur Thapa, Bist, Ganesh, Shrestha, Aarajana, Thapa, Pritam, Na, Younghwa, Kwon, Youngjoo, Lee, Eung-Seok

Journal:

Bioorganic & Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2015

44

Topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines

Karki, Radha, Song, Chanju, Kadayat, Tara Man, Magar, Til Bahadur Thapa, Bist, Ganesh, Shrestha, Aarajana, Na, Younghwa, Kwon, Youngjoo, Lee, Eung-Seok

Journal:

Bioorganic & Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2015

45

Licochalcone F alleviates glucose tolerance and chronic inflammation in diet-induced obese mice through Akt and p38 MAPK

Bak, Eun-Jung, Choi, Kyung-Chul, Jang, Sungil, Woo, Gye-Hyeong, Yoon, Ho-Geun, Na, Younghwa, Yoo, Yun-Jung, Lee, Youngseok, Jeong, Yangsik, Cha, Jeong-Heon

Journal:

Clinical Nutrition

Année:

2015

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2015

46

Quinone-cyclized Porfiromycins

Kohn, Harold, Na, Younghwa

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 172 KB

english, 2001

47

Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents

Thapa, Pritam, Jun, Kyu-Yeon, Kadayat, Tara Man, Park, Chanmi, Zheng, Zhi, Thapa Magar, Til Bahadur, Bist, Ganesh, Shrestha, Aarajana, Na, Younghwa, Kwon, Youngjoo, Lee, Eung-Seok

Journal:

Bioorganic & Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2015

48

Design and development of the helicity injection system in Versatile Experiment Spherical Torus

Park, JongYoon, An, Younghwa, Jung, Bongki, Lee, Jeongwon, Lee, HyunYoung, Chung, Kyoung-Jae, Na, Yong-Su, Hwang, Y.S.

Journal:

Fusion Engineering and Design

Année:

2015

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2015

49

Selective PCAF inhibitor ameliorates cognitive and behavioral deficits by suppressing NF-κB-mediated neuroinflammation induced by Aβ in a model of Alzheimer's disease

Park, Soo-Yeon, Kim, Mi-Jeong, Kim, Young, Lee, Yoo-Hyun, Bae, Donghyuk, Kim, Sunoh, Na, Younghwa, Yoon, Ho-Geun

Journal:

International Journal of Molecular Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2015

50

Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines

Kadayat, Tara Man, Park, Seojeong, Jun, Kyu-Yeon, Magar, Til Bahadur Thapa, Bist, Ganesh, Shrestha, Aarajana, Na, Younghwa, Kwon, Youngjoo, Lee, Eung-Seok

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2016

Langue:

english

Fichier:

PDF, 515 KB

english, 2016